Karela offers a host of medicinal benefits and is a key herb in Ayurvedic medicine.As an Antidiabetic, Karela helps support normal blood sugar levels.It possesses antioxidant properties which help in reducing the risk of diabetic complications by scavenging free radical. Working as an Hepatoprotective, the extract is found to significantly increase the active liver enzymes.

The juice of the plant is also helpful in treating alcohol-induced hepatotoxicity. As a Hypolipidemic, the compounds in Karela improve lipid profiles. As a Antipsoriatic, Karela inhibits the enzyme guanylate cyclase, which may benefit people with psoriasis. Karela also acta as an adjuvant in diabetes mellitus.